Post by Tony Held on Oct 12, 2017 15:56:37 GMT -6
Levophed in Sepsis- Episode 6
Why oh why is Levophed the wonder drug in sepsis? What's the low-down on sepsis anyway? Get those answers and more.
Podcast Notes are here
Sources:
Pathophysiology of sepsis.
Jacobi J
Am J Health Syst Pharm. 2002 Feb 15;59 Suppl 1:S3-8.
Critical Care Transport, 1st Ed.
America Academy of Orthopaedic Surgeons, UMBC, American College of Emergency Physicians
Jones & Bartlett Learning
Diastolic dysfunction and mortality in early severe sepsis and septic shock: a prospective, observational echocardiography study.
Brown SM, Pittman JE, Hirshberg EL, et al.
Critical Ultrasound Journal. 2012;4(1):8
Ketamine can cause rapid cardiovascular collapse
Kris Thompson
CBCEMP. 2017 Jan 11
Sepsis-Associated Disseminated Intravascular Coagulation and Thromboembolic Disease.
Semeraro N, Ammollo CT, Semeraro F, Colucci M.
Mediterranean Journal of Hematology and Infectious Diseases. 2010;2(3):e2010024.
Sepsis and disseminated intravascular coagulation
Kohji Okamoto, Toshihisa Tamura and Yusuke Sawatsubashi
Journal of Intensive Care 2016 4:23
New diagnostic strategy for sepsis-induced disseminated intravascular coagulation: a prospective single-center observational study
Hiroyasu Ishikura, Takeshi Nishida, Akira Murai, Yoshihiko Nakamura, Yuhei Irie, Junichi Tanaka and Takehiro Umemura
Critical Care 2014 18:R19
Vasopressors for septic shock
PulmCCM. 2013 Sep 13
Vasopressor and Inotropic Management Of Patients With Septic Shock.
Pollard S, Edwin SB, Alaniz C.
Pharmacy and Therapeutics. 2015;40(7):438-450.
Use of Antihypotensive Medications in Shock Patients
Robert Girardeau
JEMS. 2014 Sep 15
Dopamine versus norepinephrine in the treatment of septic shock: a meta-analysis.
De Backer D, Aldecoa C, Njimi H, Vincent JL
Crit Care Med. 2012 Mar;40(3):725-30. doi: 10.1097/CCM.0b013e31823778ee.
Digital necrosis: a potential risk of high-dose norepinephrine
Rafael Daroca-Pérez and Miguel F Carrascosa
Ther Adv Drug Saf. 2017 Aug; 8(8): 259-261
Vasopressin deficiency contributes to the vasodilation of septic shock.
Circulation. 1997 Mar 4;95(5):1122-5.
Landry DW, Levin HR, Gallant EM, Ashton RC Jr, Seo S, D'Alessandro D, Oz MC, Oliver JA
Factors Associated with Blood Culture Contamination in the Emergency Department: Critical Illness, End-Stage Renal Disease, and Old Age
Chih-Jan Chang, Chi-Jung Wu, Hsiang-Chin Hsu, Chiu-Hui Wu, Fang-Ying Shih, Shou-Wen Wang, Yi-Hui Wu, Chia-Ming Chang, Yi-Fang Tu, Chih-Hsien Chi, Hsin-I Shih
Public Library of Science ONE. 2015 Oct 8
Contaminated or Not? Guidelines for Interpretation of Positive Blood Cultures
Mevlin P. Weinstein
Patient Safety Network, AHRQ. 2008
Understanding lactate in sepsis & Using it to our advantage
Josh Farkas
PulmCrit. 2015 July 5
Sepsis-associated hyperlactatemia
Mercedes Garcia-Alvarez, Paul Marik, and Rinaldo Bellomo
Critical Care. 2014 18:503, 2014
Why oh why is Levophed the wonder drug in sepsis? What's the low-down on sepsis anyway? Get those answers and more.
Podcast Notes are here
Sources:
Pathophysiology of sepsis.
Jacobi J
Am J Health Syst Pharm. 2002 Feb 15;59 Suppl 1:S3-8.
Critical Care Transport, 1st Ed.
America Academy of Orthopaedic Surgeons, UMBC, American College of Emergency Physicians
Jones & Bartlett Learning
Diastolic dysfunction and mortality in early severe sepsis and septic shock: a prospective, observational echocardiography study.
Brown SM, Pittman JE, Hirshberg EL, et al.
Critical Ultrasound Journal. 2012;4(1):8
Ketamine can cause rapid cardiovascular collapse
Kris Thompson
CBCEMP. 2017 Jan 11
Sepsis-Associated Disseminated Intravascular Coagulation and Thromboembolic Disease.
Semeraro N, Ammollo CT, Semeraro F, Colucci M.
Mediterranean Journal of Hematology and Infectious Diseases. 2010;2(3):e2010024.
Sepsis and disseminated intravascular coagulation
Kohji Okamoto, Toshihisa Tamura and Yusuke Sawatsubashi
Journal of Intensive Care 2016 4:23
New diagnostic strategy for sepsis-induced disseminated intravascular coagulation: a prospective single-center observational study
Hiroyasu Ishikura, Takeshi Nishida, Akira Murai, Yoshihiko Nakamura, Yuhei Irie, Junichi Tanaka and Takehiro Umemura
Critical Care 2014 18:R19
Vasopressors for septic shock
PulmCCM. 2013 Sep 13
Vasopressor and Inotropic Management Of Patients With Septic Shock.
Pollard S, Edwin SB, Alaniz C.
Pharmacy and Therapeutics. 2015;40(7):438-450.
Use of Antihypotensive Medications in Shock Patients
Robert Girardeau
JEMS. 2014 Sep 15
Dopamine versus norepinephrine in the treatment of septic shock: a meta-analysis.
De Backer D, Aldecoa C, Njimi H, Vincent JL
Crit Care Med. 2012 Mar;40(3):725-30. doi: 10.1097/CCM.0b013e31823778ee.
Digital necrosis: a potential risk of high-dose norepinephrine
Rafael Daroca-Pérez and Miguel F Carrascosa
Ther Adv Drug Saf. 2017 Aug; 8(8): 259-261
Vasopressin deficiency contributes to the vasodilation of septic shock.
Circulation. 1997 Mar 4;95(5):1122-5.
Landry DW, Levin HR, Gallant EM, Ashton RC Jr, Seo S, D'Alessandro D, Oz MC, Oliver JA
Factors Associated with Blood Culture Contamination in the Emergency Department: Critical Illness, End-Stage Renal Disease, and Old Age
Chih-Jan Chang, Chi-Jung Wu, Hsiang-Chin Hsu, Chiu-Hui Wu, Fang-Ying Shih, Shou-Wen Wang, Yi-Hui Wu, Chia-Ming Chang, Yi-Fang Tu, Chih-Hsien Chi, Hsin-I Shih
Public Library of Science ONE. 2015 Oct 8
Contaminated or Not? Guidelines for Interpretation of Positive Blood Cultures
Mevlin P. Weinstein
Patient Safety Network, AHRQ. 2008
Understanding lactate in sepsis & Using it to our advantage
Josh Farkas
PulmCrit. 2015 July 5
Sepsis-associated hyperlactatemia
Mercedes Garcia-Alvarez, Paul Marik, and Rinaldo Bellomo
Critical Care. 2014 18:503, 2014