|
Post by Tony Held on Mar 14, 2017 21:59:23 GMT -6
CBCEMP Study Session #6Mar 23rd at 1930Hyvee - Market Grille Express 25 Conley Rd Columbia, MO Toxicology Mediator Sylvia Tribble Hope to see you there!
|
|
|
Post by silvia on Mar 23, 2017 18:33:11 GMT -6
|
|
|
Post by Tony Held on Apr 2, 2017 17:03:05 GMT -6
CBCEMP Study Session #6 ToxicologyMediator Sylvia Tribble Lecture recording is hereAttendees: Tony Held and Sylvia Tribble
|
|
|
Post by silvia on Apr 7, 2017 8:02:37 GMT -6
That was a fun topic to chat on, but I love toxicology, so any discussion on the mysteries of poisons is interesting to me. Something to think about: real life toxicology happening in our news today... Syrian attack with sarin gas. That is a poison that affects our nervous system in devastating ways. The following is a quote pulled from the internet, which summarizes its actions more eloquently than I can: " Specifically, sarin is a potent inhibitor of acetylcholinesterase, an enzyme that degrades the neurotransmitter acetylcholine after it is released into the synaptic cleft. In vertebrates, acetylcholine is the neurotransmitter used at the neuromuscular junction, where signals are transmitted between neurons from the central nervous systems to muscle fibres. Normally, acetylcholine is released from the neuron to stimulate the muscle, after which it is degraded by acetylcholinesterase, allowing the muscle to relax. A build-up of acetylcholine in the synaptic cleft, due to the inhibition of cholinesterase, means the neurotransmitter continues to act on the muscle fibre, so that any nerve impulses are effectively continually transmitted."
soooooo.... in light of what we talked about on that last study group, think about the autonomic and somatic nervous system, how this affects the patient, what symptoms would we see (sadly, we can see on the videos from Syria). Treatment is similar to organophosphate poisonings... atropine, and Pradidoxime. It is so sad that we have this happening in our world today, and I am not trying to get into politics. But I do want to use this event as a way to connect our efforts at improving our education to real life situations we can learn from.
I hope none of us ever has to come face to face with this deadly poison, but take a moment to review your haz mat data on what you would do to keep yourself safe from its grip. What would you look for to verify the assaultive agent, and subsequently chose a treatment.
|
|